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Symbol
Name
ID
Smo
smoothened, frizzled class receptor
MGI:108075
Phenotype annotations related to respiratory system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
respiratory system phenotype
nasal bone hypoplasia
nasal septum hypoplasia
abnormal thyroid cartilage morphology
abnormal bronchioalveolar stem cell morphology
decreased type II pneumocyte number
abnormal pulmonary alveolus morphology
overexpanded pulmonary alveolus
emphysema
Availability Mouse Genotype
Gli1tm3(cre/ERT2)Alj/Gli1+
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sor+  (conditional)
*
Gli2tm1(cre/ERT2)Tipe/Gli2+
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sor+  (conditional)
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sor+
Tg(Pdgfra-cre/ERT)467Dbe/0  (conditional)
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sor+
Ndor1Tg(UBC-cre/ERT2)1Ejb/0  (conditional)
Smotm1Amc/Smotm2Amc
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory